Found 42 matching trials
Evaluation of BH4 Responsiveness in Our PKU Patients
PHASE1This study aims to evaluate BH4 responsiveness in our PKU patients and to c...
Status
Active Not Recruiting
Location
Sohag Faculty of Medicine
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
PHASE1This project will evaluate the impact of L-Citrulline, tetrahydrobiopterin ...
Location
VA Salt Lake City Health Care System, Salt Lake City, UT
Study to Evaluate the Safety and Efficacy of Phenoptin™ in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels
PHASE3The primary objective of this study is to evaluate the efficacy of Phenopti...
Location
Multiple Locations
A Study of the Effects of 6R-BH4 on Blood Pressure in Subjects With Poorly Controlled Systemic Hypertension
PHASE2The purpose of this study is to determine whether 6R-BH4 (sapropterin dihyd...
Location
Multiple Locations
A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial Dysfunction
PHASE2This Phase 2, randomized, open-label, 2-treatment, 2-sequence, 2-period cro...
Location
Multiple Locations
Phase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With Phenylketonuria
PHASE3This is an open-label, non-comparative, Phase 3 study to evaluate the degre...
Location
Please contact Merck KGaA Communication Center
Tetrahydrobiopterin in Patients With Chronic Kidney Disease (CKD) and Albuminuria
PHASE2Patients with chronic kidney disease (CKD) and albuminuria are at increased...
Location
University of Michigan
Long-Term Tetrahydrobiopterin Treatment in PKU Patients of 0-18 Years - Study on Phenylalanine Tolerance and Safety
PHASE2The aim of the study is to confirm the efficacy and safety of BH4 in the tr...
Location
Multiple Locations
Cystic Fibrosis and Endothelial Function: At Rest and During Exercise
PHASE2Perhaps one of the most disturbing aspects of Cystic Fibrosis (CF) is the a...
Location
Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology
Long Term Nitric Oxide Bioavailability on Vascular Health in Chronic Obstructive Pulmonary Disease
PHASE2Chronic obstructive pulmonary disease (COPD) affects up to 14 million peopl...
Location
Georgia Prevention Institute